home
people and institutions- projects and publications
events-
conferences &
seminar days - colloquia
- imprint
Forecasting Evolution?
CONFERENCE SCHEDULE
Wednesday, July 8
| 14:00 | Registration and refreshments |
| 14:30 – 14:45 |
Welcome address Jonathan Howard Opening remarks Michael Lässig |
14:45 – 17:45 |
Session 1: Microbial evolution Chair: Tobias Bollenbach |
| 14:45 – 15:15 | Olivier Tenaillon Modes and tempo microbial molecular evolution |
| 15:15 – 15:45 | Michael Desai How predictable are microbial evolution experiments? |
| 15:45 – 16:00 | Arjan de Visser Chance and necessity in the evolution of an antibiotic resistance enzyme |
| 16:00 – 16:30 | Coffee Break |
| 16:30 – 16:45 | Lei Dai Repeatability in the evolution of antiviral resistance as a function of selection pressure |
| 16:45 – 17:00 | Ivana Gudelij Harbouring low virulence cheats within a pathogen population increases both fitness and virulence |
| 17:00 – 17:30 | Berenike Maier Segregation dynamics succeeding genetic variation of bacterial surface structures |
| 17:30 – 17:45 | Diogo Santos The impact of genomic rearrangements on the evolutionary path of populations |
18:00 – 20:00 |
Session 2: Posters Welcome reception |
Thursday, July 9
| 09:00 – 13:00 | Session 3: Microbial evolution Chair: Olivier Tenaillon |
| 09:00 – 09:30 |
Dan Andersson Forecasting evolution of antibiotic resistance |
| 09:30 – 09:45 | Tobias Bollenbach Quantifying the determinants of evolutionary dynamics |
| 09:45 – 10:00 | Peter Lind Experimental evolution reveals hidden diversity in evolutionary pathways |
| 10:00 – 10:30 | Roy Kishony Multi-step adaptive paths leading to high level antibiotic resistance |
| 10:30 – 11:00 | Coffee Break |
| 11:00 – 11:30 | Eugene Shakhnovich Biophysical walks on fitness landscapes |
| 11:30 – 11:45 | Daniel Klemmer Sex or simplicity: evolutionary limits to microbial complexity |
| 11:45 – 12:00 | Martin Weigt Coevolutionary inference of mutational landscapes: The case of the betalactamase TEM1 |
| 12:00 – 12:15 | Debora Marks Using evolutionary information to predict the effect of mutations |
| 12:15 – 12:30 | José Aguilar-Rodriguez The navigability of 1000 empirical adaptive landscapes of transcriptional regulation |
| 12:30 – 12:45 | Martin Lercher An adaptive scenario for the origins of complex innovations |
| 12:45 – 13:00 | Macarena Toll-Riera The genomic architecture of metabolic evolutionary innovation in Pseudomonas aeruginosa |
| 13:00 – 15:00 | Lunch Break |
15:00 – 18:00 |
Session 4: Evolution of cancer Chair: Ville Mustonen |
| 15:00 – 15:30 | Marco Gerlinger Predicting cancer progression and drug resistance evolution |
| 15:30 – 16:00 | Michael Hochberg Forecasting tumor progression and therapeutic outcomes |
| 16:00 – 16:30 | Sohrab Shah Tracking clonal dynamics in human cancers in space and time at single cell resolution |
| 16:30 – 17:00 | Coffee Break |
| 17:00 – 17:30 | Leonid Mirny A tug-of-war between driver and passenger mutations in cancer |
| 17:30 – 17:45 | Christopher McFarland The role of passenger mutations in cancer |
| 17:45 – 18:00 | Andreas Beyer Genome structure determines tumor evolution |
18:10 – 19:00 |
Session 5: Keynote Chair: Isabel Gordo Richard Lenski Time travel in experimental evolution |
Friday, July 10
| 09:00 – 12:30 | Session 6: Viral evolution Chair: Georgii Bazykin |
| 09:00 – 09:30 | Jesse Bloom Mapping constraints on the evolution of influenza |
| 09:30 – 10:00 | Christopher Illingworth Assessing the predictability of within-host influenza infection |
| 10:00 – 10:15 | Adi Stern Parallel evolution of vaccine-derived polioviruses, from bioinformatics to the bench: predictability of a viral epidemic |
| 10:15 – 10:45 | Colin Russell Challenges in predicting influenza virus evolution |
| 10:45 – 11:15 | Coffee Break |
| 11:15 – 11:45 | Marta Łuksza Integrating genetics, phylogenetics and epidemiology in evolutionary predictions |
| 11:45 – 12:15 | Trevor Bedford Real-time evolutionary forecasting |
| 12:15 – 12:30 | Gytis Dudas Population genetics of Ebola virus in West Africa |
| 12:30 - 14:30 | Lunch Break |
| 14:30 - 15:30 | Session 6: Viral evolution (cont‘d) |
| 14:30 – 15:00 | Arup Chakraborty Predicting HIV fitness landscapes to guide vaccine design |
| 15:00 – 15:30 | Richard Neher Exploration of sequence space by HIV-1 populations |
15:30 – 17:15 |
Session 7: Evolution of the immune system Chair: Jakub Otwinowski |
| 15:30 – 16:00 | Aleksandra Walczak Diversity generation in immune receptor repertoires |
| 16:00 – 16:30 | Sarah Cobey Evolvability in antibody repertoires |
| 16:30 – 17:00 | Coffee Break |
| 17:00 – 17:15 | Simona Cocco Innate immune driven host and virus evolution |
| 17:15 – 17:45 | Armita Nourmohammad Adaptation of molecular traits: from gene expression to antibody-viral interaction |
17:45 – 18:30 |
Session 8: Theoretical links Chair: Armita Nourmohammad |
| 17:45 – 18:15 | Daniel Fisher Evolutionary dynamics in high dimensions |
| 18:15 – 18:30 | Joachim Krug Absence of adaptive pathways in fitness landscapes with sparse genetic interactions |
| 19:00 | Dinner Excursion |
Saturday, July 11
| 09:00 – 09:30 | Session 8: Theoretical links (cont‘d) |
| 09:00 – 09:30 | Boris Shraiman The challenges of predictive theory |
09:30 – 12:30 |
Session 9: Evolution and ecology Chair: Michael Hochberg |
| 09:30 – 10:00 | Michael Doebeli Predicting the dynamics of adaptive diversification in microbial communities using genome-based metabolic models |
| 10:00 – 10:30 | Stanislas Leibler Strongly deterministic population dynamics in closed microbial communities |
| 10:30 – 11:00 | Coffee Break |
| 11:00 - 11:15 | Ana Sousa The repeatability of Escherichia coli evolution in its natural environment |
| 11:15 – 11:30 | Juliette de Meaux Tracking signatures of natural selection on patterns of of cis-regulatory divergence in the Arabidopsis genus |
| 11:30 – 12:00 | Luke Mahler Replicated macroevolutionary radiations on Simpsonian adaptive landscapes |
| 12:00 – 12:30 | Natalia Komarova Evolution, space, cooperation |
12:30 |
Closing remarks Ville Mustonen |